Wall motion estimation in intracranial aneurysms

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چکیده

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Intracranial Aneurysms: Wall Motion Analysis for Prediction of Rupture.

Intracranial aneurysms are a common pathologic condition with a potential severe complication: rupture. Effective treatment options exist, neurosurgical clipping and endovascular techniques, but guidelines for treatment are unclear and focus mainly on patient age, aneurysm size, and localization. New criteria to define the risk of rupture are needed to refine these guidelines. One potential can...

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CFD Analysis Incorporating the Influence of Wall Motion: Application to Intracranial Aneurysms

Haemodynamics, and in particular wall shear stress, is thought to play a critical role in the progression and rupture of intracranial aneurysms. A novel method is presented that combines image-based wall motion estimation obtained through non-rigid registration with computational fluid dynamics (CFD) simulations in order to provide realistic intra-aneurysmal flow patterns and understand the eff...

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Flow instability and wall shear stress variation in intracranial aneurysms.

We investigate the flow dynamics and oscillatory behaviour of wall shear stress (WSS) vectors in intracranial aneurysms using high resolution numerical simulations. We analyse three representative patient-specific internal carotid arteries laden with aneurysms of different characteristics: (i) a wide-necked saccular aneurysm, (ii) a narrower-necked saccular aneurysm, and (iii) a case with two a...

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Intracranial Aneurysms: Connecting Hemodynamics, Biomechanics and Wall Characteristics

Increased detection of incidental unruptured intracranial aneurysms has made the clinical decision making process and management of patients with this disease more challenging since the risk of complications of surgical and endovascular interventions can easily exceed the aneurysms’ natural risk of rupture. On the other hand, because aneurysm rupture and subsequent subarachnoid hemorrhage have ...

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Wall Mechanical Properties and Hemodynamics of Unruptured Intracranial Aneurysms.

BACKGROUND AND PURPOSE Aneurysm progression and rupture is thought to be governed by progressive degradation and weakening of the wall in response to abnormal hemodynamics. Our goal was to investigate the relationship between the intra-aneurysmal hemodynamic conditions and wall mechanical properties in human aneurysms. MATERIALS AND METHODS A total of 8 unruptured aneurysms were analyzed. Com...

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ژورنال

عنوان ژورنال: Physiological Measurement

سال: 2010

ISSN: 0967-3334,1361-6579

DOI: 10.1088/0967-3334/31/9/004